Even though niacin is extremely important for many bodily functions, you can develop an niacin allergy . Some of the effects of niacin come from the release of histamine in the body. While many people have an initial reaction to niacin, after taking it for a short period, the reaction tends to diminish and disappear. Those with a niacin allergy, however, only see an increase in symptoms and may experience more far-reaching and severe allergic reactions.
Signs & Symptoms of a Allergy to Niacin
One of the most frequent reactions caused by niacin is flushing. Flushing comes from the dilation of blood vessels caused by the release of histamine in the body. The skin may feel warm and itchy or it just may be red. This can lead to inflammation of the skin.
Niacin is also important in the processing of carbohydrates. When carbohydrates break down, it forms sugar. If the niacin performs too well, it can create too much sugar and increase the blood sugar levels dramatically. This may be dangerous for those suffering from diabetes.
Gout occurs when the body has a build up of uric acid. It's a form of arthritis caused by the crystals in the joint. The crystals make the joints painful and inflamed. Too high of intake of niacin may be one cause of gout. If your doctor put you on niacin to reduce cholesterol and plaque formation, you might find that it also increases the formation of uric acid, thus causing gout. This can occur if you take three grams per day or more.
High doses of niacin or normal doses in someone sensitive to niacin can create other problems such as vision problems and liver problems. It also can cause an irregular heartbeat, loss of vision and stomach problems such as ulceration of the digestive tract. Since niacin increases metabolism, you have the potential to increase it beyond control creating stresses on the digestive system. This stress can lead to another symptom of a niacin allergy, stomach ulcers.
Traditional Allergic Reactions Caused by Niacin
Just like any other allergen, you might experience some traditional allergic reactions. These can include dizziness, dry skin, sweating and gas. You might find you have insomnia or experience cramping of the leg muscles. Nausea may become a problem as well as chronic belching.
More severe signs of a niacin allergy include problems breathing, hives, and swelling of the face, throat, lips or tongue. It can set off an uneven heartbeat that feels like it's pounding out of your chest. It may cause jaundice, a yellowing of the eyes and skin, flu-like symptoms, fever and weakness.
You might find that your urine is darker. Extreme reactions also include excess bleeding from the nose, digestive tract and gums. You might experience fainting or blood clot formation. Leg pain and rashes are indicators of a blood clot. These symptoms occur because niacin increases the production of histamine and higher histamine levels cause the blood vessels to dilate.
If you notice any of the symptoms of a niacin allergy or reaction and are taking increased dosages of niacin, contact your physician immediately.